Reactions of Rabbits to Intracutaneous Injec- Tions of Pneumococci and Their Products v. the Development of Eye Reactivity to Derivatives of Pneumococci by Louis A. Julianelle, Ph.d
نویسنده
چکیده
Methods.--The injection of rabbits with Pneumococcus or its derivatives was carried out as described in a previous communication (1). Eye Test.--Eye tests were done according to the technique described by Derick and Swift (3, 4). The cornea was anesthetized with one drop of 10 per cent novocaine, and then it was lightly scarified with a cataract knife. Three scratches were made on one of the upper quadrants of the cornea beginning 1 to 2 mm. from the sclerocorneal junction and reaching to the center. One drop of the reagent was instilled into the conjunctival sac and the material was rubbed gently over the surface of the cornea by manipulation of the lid. Rabbits received from 8 to 12 intracutaneous injections of bacterial suspension. About 20 days after the |ast injection eye tests were performed by dropping into the eye, prepared as previously described, one drop of a solution of "nucleoprotein" (2). For purpose of control, two drops of the same solution were dropped into one of the eyes of each of a series of normal rabbits.
منابع مشابه
REACTIONS OF RABBITS TO INTRACUTANEOUS INJEC- TIONS OF PNEUMOCOCCI AND THEIR PRODUCTS IV. THE DEVELOPMENT OF SKIN REACTIVITY TO DERIVATIVES OF PNELr~OCOCCUS BY LOUIS A. JULIANELLE, PH.D
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